For a summary of the risks associated with an investment in BlackRock Multi-Sector Opportunities Trust (“the Trust”), please see the “Risks” section of the Trust’s preliminary prospectus. The information in the Trust’s preliminary prospectus and in this material is not complete and may be amended or changed. A registration statement, which includes the preliminary prospectus, relating to these securities has been filed with the Securities and Exchange Commission (“SEC”), but has not yet become effective. We may not sell these securities until the registration statement filed with the SEC is effective. This material is not an offer to sell securities of the Trust and is not a solicitation of an offer to buy securities of the Trust in any jurisdiction where the offer or sale is not permitted. Investors should consider the Trust’s investment objective, risks, charges and expenses carefully before investing. Copies of the preliminary prospectus may be obtained by contacting BlackRock at (800) 882-0052. The preliminary prospectus contains more complete information about the Trust and should be read carefully before investing. A copy of the final prospectus can be obtained from BlackRock at (800) 882-0052, when available. The final prospectus, when available, should be read and considered carefully before investing. BlackRock Investments LLC, an affiliate of the Trust and the Trust’s investment “adviser,” acts as distributor for the Trust’s shares.